Flashback: High antidepressant dose linked to self harm in youths | WHAT REALLY HAPPENED


Flashback: High antidepressant dose linked to self harm in youths

For the study, Miller and colleagues looked at the health records of 162,625 privately insured people ages 10 to 64 treated for depression with three popular antidepressants best known by the brand names Celexa, Prozac and Zoloft.

They compared otherwise similar patients — based on the intensity of their depression symptoms, previous self harm and other factors — who got either typical starting doses or higher doses.

The typical starting doses were 20 mg. a day for Celexa and Prozac and 50 mg. a day for Zoloft.

Result: After a year, children, teens and young adults were twice as likely to engage in deliberate self harm if they started at higher doses. Such acts were especially common in the first three months. No such link between starting dose and self harm was found in adults 25 and up.

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