If the US and its "coalition" are, in fact, covering for ISIS, then the end for that is near. Russia issued new Rules of Engagement today, instructing its air forces and Surface-to-Air missile batteries that they are to shoot down any aircraft threatening Syrian Army forces.
So the next "mistake" by a US pilot, will very likely be the last mistake that pilot makes. Once the S-300 anti-aircraft missile system "locks-on" to an aircraft, there is no escape and no defense. The system cannot be jammed and its missiles cannot be fooled by flares or chaff. An S-300 absolutely, positively, will hit and kill any aircraft it is fired at.
This is also bad news for Turkey, which also has troops and planes operating inside Syria without permission. If a Turk aircraft attacks a Syrian Army unit, it, too, will be shot down.
Israel is also in trouble with these news rules of engagement. Israel has been sending the Israeli Air Force to strike areas of the occupied Golan Heights – official Syrian territory. Israeli jets will now be shot down if they attack a Syrian Army position.