Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers | WHAT REALLY HAPPENED

Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers

Researchers in Japan have conducted a study suggesting that the B.1.617 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in India has evolved a unique strategy to facilitate infection and evade the immunity induced by vaccination or natural infection.

The SARS-CoV-2 virus is the agent responsible for the coronavirus disease 2019 (COVID-19 ) pandemic that continues to threaten global public health and the worldwide economy.

Bioinformatic analyses revealed that the mutation P681R is highly conserved in the viral spike protein of the B.1.617 lineage. The spike protein mediates the initial stage of the infection process when its receptor-binding domain (RBD) attaches to the host cell receptor angiotensin-converting enzyme 2 (ACE2).

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